S100 monoclonal antibodies – epitope specificity

Study of epitope specificity
We have participated in ISOBM workshop TD-11 for epitope mapping of different anti-S100 mAbs. Our part was 1) the cross inhibition studies and 2) IHC studies

Application of anti-S100 mAbs for immunohistochemistry
Anti-S100 from ISOBM TD11 workshop or provided by HyTest Ltd., Finland, were used for immunostaining of human brain tissue. The IHC pictures can be seen below

Example 1: HyTest mAb 6G1 / human brain / neurones

mAb isobm365 (20.1, E.Paus, Norwegian Radium Hospital) /human brain /blood vessel wall